What is a common symptom of Tuberous Sclerosis Complex?

Tuberous Sclerosis Complex (TSC) is a genetic disorder characterized by the growth of non-cancerous tumors in various organs, including the brain, skin, kidneys, and lungs. One of the hallmark symptoms of TSC is the presence of skin lesions, such as hypopigmented macules, angiofibromas, or shagreen patches. These skin manifestations are often one of the first signs that lead to the diagnosis of TSC in children.

In addition to skin lesions, seizures are another common symptom associated with TSC. Seizures may occur due to the presence of tubers, which are abnormal growths in the brain that can disrupt normal electrical activity. The combination of skin lesions and seizures is quite distinctive for Tuberous Sclerosis Complex, making it a key aspect of the disease for healthcare professionals to recognize and address during diagnosis and management.

While chronic headaches, visual impairment, and muscle stiffness can be associated with various neurological conditions, they are not characteristic symptoms of Tuberous Sclerosis Complex. In this context, skin lesions and seizures represent the most common and defining features of the disorder.