What is the first-line treatment for pediatric migraine?

Acetaminophen or ibuprofen is recognized as the first-line treatment for pediatric migraines due to their effectiveness and safety profile. These over-the-counter medications are commonly used to relieve mild to moderate migraine pain in children. They work by reducing inflammation and blocking pain signals in the brain, which are key factors in migraine pathophysiology.

For many children experiencing their first migraine episode, these medications can provide adequate relief, especially when taken early in the course of the headache. Studies have shown that prompt treatment with acetaminophen or ibuprofen can effectively reduce the severity and duration of migraine attacks.

In contrast, other options such as aspirin are generally avoided in children due to the risk of Reye's syndrome, a serious condition that can cause liver and brain damage. Corticosteroids, while useful for certain conditions, are not typically employed as first-line treatments for migraine attacks in pediatric patients due to their side effects and the availability of safer alternatives. Topiramate is a preventative medication and may be used in cases of frequent or severe migraines, but it is not the initial treatment option for acute migraine episodes.