What is the lifespan outlook for a child diagnosed with Duchenne Muscular Dystrophy?

A child diagnosed with Duchenne Muscular Dystrophy (DMD) typically faces a reduced life expectancy, often extending into the mid-20s. DMD is a progressive neuromuscular disorder characterized by muscle degeneration and weakness due to the absence of dystrophin, a protein essential for muscle function. This condition primarily affects boys and leads to significant complications, particularly respiratory and cardiac issues, which are the main contributors to decreased life expectancy.

Over the years, advancements in medical care and supportive therapies have improved the lifespan of individuals with DMD. However, even with treatment, the progressive nature of the disease can lead to severe muscle impairments that complicate health. As respiratory muscles weaken, the risk of respiratory failure increases, making it a pivotal factor in the life expectancy of those affected. The introduction of interventions such as assisted ventilation and cardiac care can prolong life and improve quality, but the overall outlook remains significantly altered compared to the general population.

Understanding the trajectory of DMD allows for better planning and management of care, although it remains essential to be aware that while life expectancy has improved, it is generally not normal and does tend to decrease.